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Pattern of bacterial colonization of atopic dermatitis in saudi children

Jalal Ali Bilal1, Mohammad Issa Ahmad, Ahmad A Al Robaee

  • 1Department of Paediatrics, College of Medicine, Qassim University , Buraydah, Saudi Arabia .

Journal of Clinical and Diagnostic Research : JCDR
|November 2, 2013
PubMed

Insights

Bacterial colonization is common in children with atopic dermatitis, with gram-negative bacteria and specific species like Staphylococcus aureus significantly present on lesions. These findings highlight potential complications in pediatric atopic dermatitis management.

Area of Science:

  • Dermatology
  • Microbiology
  • Pediatrics

Background:

  • Atopic dermatitis is a common inflammatory skin condition in children.
  • Infections by microorganisms can complicate atopic dermatitis, particularly in pediatric cases.

Purpose of the Study:

  • To investigate and determine the prevalence of bacterial colonization in children diagnosed with atopic dermatitis.
  • To compare bacterial presence on lesional versus non-lesional skin in pediatric patients.

Main Methods:

  • A cohort of 80 children with atopic dermatitis was enrolled.
  • Bacterial samples were collected from both eczematous lesions and healthy skin sites.
  • Bacterial identification utilized colonial morphology, Gram staining, and the Vitek System.

Main Results:

  • Gram-positive cocci were prevalent on both lesional (97.5%) and non-lesional (96.2%) skin.
  • Staphylococci species, Enterococci (Ent. Faecalis, Ent. Faecium, Ent. gallinarium), and Corynebacterium species were significantly more abundant on atopic dermatitis lesions.
  • Gram-negative bacteria, including Pantoea agglomerans and Enterobacter cloacae, were identified on lesions but not on healthy skin.

Conclusions:

  • Atopic dermatitis in children is frequently complicated by streptococcal and gram-negative bacterial colonization.
  • The presence of gram-negative bacteria correlated with the severity of atopic dermatitis lesions.
  • While Staphylococcus aureus is a primary inhabitant, Enterococci and Corynebacterium species are significant residents; no direct causal link to atopic dermatitis was established.
Abstract

Keywords:
AtopicBacteriaChildDermatitisSaudi Arabia

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