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Related Concept Videos

Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Inflammatory Bowel Disease III: Crohn's Disease01:25

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Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
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Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

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Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
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Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Related Experiment Video

Updated: May 6, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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Update in pediatric inflammatory bowel disease.

Shervin Rabizadeh1, Marla Dubinsky

  • 1Department of Pediatrics, Pediatric Inflammatory Bowel Disease Center, Cedars-Sinai Medical Center, 8635 West 3rd Street, Suite 1165W, Los Angeles, CA 90048, USA.

Rheumatic Diseases Clinics of North America
|November 5, 2013
PubMed
Summary

Pediatric inflammatory bowel disease (IBD) is increasing, affecting children physically and psychologically. Management requires individualized approaches due to unique pediatric IBD aspects.

Keywords:
Crohn diseaseInflammatory bowel diseasePediatricsUlcerative colitis

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Area of Science:

  • Pediatric gastroenterology
  • Inflammatory Bowel Disease (IBD) research

Background:

  • Rising incidence of pediatric inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis.
  • Children with IBD face unique physical and psychosocial challenges, increasing vulnerability.
  • Standard adult IBD protocols may not adequately address pediatric-specific needs.

Purpose of the Study:

  • To review the unique aspects of pediatric IBD.
  • To discuss the implications for diagnosing and managing IBD in children.
  • To emphasize the need for individualized pediatric IBD care.

Main Methods:

  • Literature review focusing on pediatric IBD.
  • Analysis of studies comparing pediatric and adult IBD cases.
  • Synthesis of current diagnostic and management strategies for pediatric IBD.

Main Results:

  • Pediatric IBD presents distinct clinical features and disease courses.
  • Psychosocial morbidities are significant in pediatric IBD patients.
  • Age-specific considerations are crucial for effective IBD management in children.

Conclusions:

  • Individualized management is essential for pediatric IBD.
  • Early and accurate diagnosis impacts long-term outcomes.
  • Further research into pediatric-specific IBD treatments is warranted.