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Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
Epidemiology of moderate preterm, late preterm and early term delivery
Cande V Ananth1, Alexander M Friedman, Cynthia Gyamfi-Bannerman
1Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, 622 West 168th Street, New York, NY 10032, USA; Department of Epidemiology, Joseph L. Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA.
Abstract:
Moderate preterm, late preterm, and early term deliveries represent a major and growing public health concern. These deliveries are associated with significant financial burden and pose serious risks to mothers and newborns. Women who deliver at moderate and late gestational ages in one pregnancy are at increased risk of delivering at these gestational ages, or earlier, in a subsequent pregnancy. Births in moderate preterm and late preterm gestational ages are associated with significant infant morbidity and mortality. Efforts to reduce deliveries in moderate preterm and late preterm gestations and interventions designed to ameliorate the problems in infants delivered at the gestational ages may be targets worthy of future investigation.
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