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Published on: September 20, 2018
Neuro-Bechet`s Disease: A clinical review
1Department of Neurology, King Hussein Medical Center, Amman, Jordan. Fax. +962 (6) 533 7987/534 9896.
Objective:
To assess the neurological complications of Behcet`s disease among Jordanian patients, and to relate these complications with the presence of antiphospholipid antibodies.
Methods:
Twenty-two patients with Neuro-Behcet`s disease admitted to King Hussein Medical Center, Amman, Jordan between January 1997 and August 1999, were evaluated clinically and by neuroimaging techniques. There were 17 males (77%), 5 females (23%), with a mean age of 36 years (range 18-51). Antiphospholipid antibodies were tested in all the patients.
Results:
Brain infarcts were seen in 18 cases; 12 in the anterior fossa, 6 in the posterior fossa, and 2 patients had spinal cord ischemia. Five patients had sinus thrombosis; 4 in the superior sagittal sinus, one in the sigmoid sinus, all were proved by magnetic resonance venogram. All patients were tested for antiphospholipid antibodies and showed negative results.
Conclusion:
Brain infarcts are the most common neurological complications of Behcet`s disease, less common is sinus thrombosis, and we found no link between these complications and the presence of antiphosphplipid antibodies.
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