[Determination of alpha 2-macroglobulin and alpha 1-antitrypsin in amniotic fluid using laser nephelometry]

By using Laser nephelometry concentration of alpha 2-macroglobulin and alpha 1-antitrypsin in amniotic fluid was measured in early pregnancy (15th-24th week) and near term (after 37th week). alpha 2-macroglobulin was demonstrable in all cases, concentration of specimen after 37th week were significantly higher than in early pregnancy. Concentration of alpha 1-antitrypsin changes during pregnancy similar to total protein and albumin concentrations.