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Updated: May 6, 2026

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
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Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum

Ingo Rekittke1, Elena Olkhova, Jochen Wiesner

  • 1Medizinische Klinik IV (Hämatologie), Justus-Liebig-Universität Giessen, Klinikstrasse 33, D-35392 Giessen, Germany.

FEBS Letters
|November 6, 2013
PubMed

Keywords:
(E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate(E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase2-C-methyl-d-erythritol-2,4-cyclo-diphosphate2-C-methyl-d-erythritol-4-phosphateDMAPPDrug designHMBPPIPPIsoprenoid biosynthesisLytBMEPMEcPPPlasmodium falciparumX-ray structuredimethylallyl diphosphateisopentenyl diphosphate

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