Related Experiment Video
Updated: May 6, 2026
13:41
Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
11.4K
Human papilloma virus vaccine associated uveitis
Henry D Holt, David M Hinkle, Naomi S Falk
1Lions Eye Institute, Albany Medical College, Slingerlands, New York, USA. hncl1983@gmail.com.
Current Drug Safety
|November 7, 2013
Summary
Human papilloma virus (HPV) vaccination may be linked to uveitis, an inflammatory eye condition. This association is considered "possible" based on case reports, prompting awareness among clinicians.
Area of Science:
- Ophthalmology
- Immunology
- Vaccinology
Background:
- The human papilloma virus (HPV) vaccine is widely administered for cervical cancer prevention.
- Uveitis is a potentially sight-threatening inflammatory condition of the eye.
Observation:
- This study analyzed 24 case reports of uveitis following HPV vaccination.
- The reported cases predominantly affected females, with a median age of 17.
- The median time from vaccination to uveitis onset was 30 days.
Findings:
- A possible association between HPV vaccination and the development of uveitis was identified.
- The World Health Organization criteria suggest a "possible" link, considering temporal relationship and dechallenge/rechallenge data.
- Bilateral uveitis and papillitis were noted in some cases.
Implications:
- Clinicians should maintain awareness of potential ocular side effects, including uveitis, after HPV vaccination.
- Further research may be warranted to elucidate the precise relationship and underlying mechanisms.
- Early recognition and management of uveitis post-vaccination are crucial for patient outcomes.
Related Concept Videos
01:30Cancer Vaccines
1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K
01:51Vaccinations
44.3K
Overview
44.3K
01:26Sexually Transmitted Infections
2.0K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
2.0K
01:27Cytomegalovirus Disease
108
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
108