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Updated: May 6, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
[Cytomegalovirus encephalitis in an HIV-negative patient]
Carla Ferreira Santos1, Marlene Delgado, Ana Bárbara Simões
1Serviço de Medicina Interna 2. Hospital de São Teotónio. Viseu. Portugal.
Abstract:
Secondary immunodeficiences are associated with an increased incidence of infection and malignancy, as well with development of autoimmune disease. Immune system function is altered by many conditions, such as aging, malnutrition and mycobacterial infections. However, the treatment of the primary condition often results in the improvement of the immune compromise. The authors present a case of cytomegalovirus encephalitis and hepatitis, due to viral reactivation associated with development of secondary immunodeficience in an HIV-negative patient.
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