Related Experiment Video
Updated: May 6, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Preoperative bowel preparation in children: polyethylene glycol versus normal saline
1Department of Surgery, Rajindra Hospital, Patiala, Punjab, India.
Insights
Polyethylene glycol (PEG) is a better option than normal saline for pediatric bowel preparation before colorectal surgery. PEG offers improved patient comfort and fewer complications with comparable costs and preparation quality.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Pharmacology
Background:
- Colorectal surgeries necessitate bowel preparation, typically using normal saline in children.
- Normal saline bowel preparation is cumbersome and causes significant patient discomfort.
- This study investigates an alternative to standard pediatric bowel preparation.
Purpose of the Study:
- To compare the efficacy and safety of polyethylene glycol (PEG) versus normal saline for preoperative bowel preparation in pediatric patients undergoing colorectal surgery.
- To assess patient and staff acceptance, complication rates, and cost-effectiveness of PEG compared to normal saline.
Main Methods:
- A randomized study involving 30 pediatric patients scheduled for colonic or colorectal surgery.
- Patients were randomly assigned to receive either polyethylene glycol (PEG) or normal saline (NS) for bowel preparation.
- Group I received PEG, and Group II received NS.
Main Results:
- No significant difference in the quality of bowel preparation between PEG and normal saline groups (P > 0.05).
- PEG was associated with significantly fewer complications (P < 0.05) and was rated as easier, more comfortable, and acceptable by patients, relatives, and staff.
- Overall costs were comparable between the two preparation methods.
Conclusions:
- Polyethylene glycol (PEG) is a safe and effective alternative for large bowel preparation in children.
- PEG offers superior patient comfort and reduced complication rates compared to normal saline.
- PEG represents a cost-effective and acceptable option for pediatric preoperative bowel preparation.
Background:
Colorectal surgeries frequently require bowel preparation. In children, (is this standard of care?: this method is mostly followed) this is usually performed using normal saline, which is very cumbersome and causes unnecessary discomfort. This study compared polyethylene glycol (PEG) with normal saline for preoperative bowel preparation in children.
Patients And Methods:
Thirty patients, admitted in the Department of Paediatric Surgery, Rajindra Hospital, Patiala, for colonic and colorectal surgical procedures, were divided into two groups, I (PEG) and II (NS), randomly for bowel preparation with PEG and normal saline, respectively.
Results:
It was found that there was no significant difference in the quality of preparation (P > 0.05), but PEG use was found to be easier, more comfortable and acceptable for the patients, their relatives and the hospital staff. Overall, complications are significantly lesser for PEG preparation (P < 0.05). There was no significant difference in the overall cost.
Conclusion:
Thus, it can be inferred that PEG may be a safe, cost-effective and acceptable option for large bowel preparation.
More Related Videos
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Drugs Affecting GI Tract Motility: Other Laxatives
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Prevention of Further Absorption of Poison
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Endoscopic Procedures II: Colonoscopy
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

