Related Experiment Video
Updated: May 6, 2026
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
[Imaging and measuring system of the accommodation of eye based on the optical coherence tomography]
Xiaopu Xu1, Xuan Yang, Haihua Zheng
1The 2nd Hospital Affiliated to Wenzhou Medical College, Wenzhou 325027. xiaopu@wz.zj.cn
Objective:
To develop a spectral-domain optical coherence tomography (SD-OCT) system, for precisely imaging the accommodation of the anterior segment of the human eye.
Methods:
Design the SD-OCT system based on two Michelson interferometer by using the basic principal of weak coherent light interference and modular design of dual channel dual focus.
Results:
The system can provide simultaneous cross-sectional imaging of all the surfaces of the anterior segment of the eye including the cornea, anterior chamber, anterior and posterior surfaces of the crystalline lens. Thus, the dynamic change of modification of the curvatures can be calculated in real time.
Conclusions:
The system was successfully tested in imaging accommodation, with high resolution and non contact. The preliminary results demonstrated the feasibility of this novel approach to measure the eye parameters.
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