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Oral conditions associated with hepatitis C virus infection

Seyed-Moayed Alavian1, Nastaran Mahboobi, Nima Mahboobi

  • 1Department of Gastroenterology and Hepatology, Baqiyatallah University of Medical Sciences, Research Center for Gastroenterology and Liver Disease, Tehran, Iran.

Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association
|November 8, 2013
PubMed

Insights

Hepatitis C virus (HCV) infection impacts millions globally. This review explores HCV

Area of Science:

  • Hepatology
  • Immunology
  • Oral Medicine

Background:

  • Hepatitis C virus (HCV) infection affects over 170 million people worldwide.
  • HCV causes not only liver disease but also various extrahepatic manifestations.
  • The link between HCV and specific oral conditions remains incompletely understood.

Purpose of the Study:

  • To review the association between Hepatitis C virus infection and various oral conditions.
  • To discuss the potential mechanisms underlying these oral manifestations.
  • To highlight the importance of recognizing oral health issues in HCV patients.

Main Methods:

  • Literature review of studies investigating Hepatitis C virus and oral conditions.
  • Analysis of reported extrahepatic manifestations related to HCV.
  • Synthesis of current understanding regarding oral health, Sjogren's syndrome, lichen planus, and oral cancer in the context of HCV.

Main Results:

  • HCV infection is linked to several extrahepatic conditions, including immune-mediated diseases.
  • Specific oral conditions, such as Sjogren's syndrome, lichen planus, and potentially oral cancer, have been recurrently associated with HCV.
  • Therapeutic interventions for HCV may also present side effects impacting oral health.

Conclusions:

  • Hepatitis C virus infection has significant systemic implications beyond liver disease.
  • Recognizing and managing oral manifestations is crucial for comprehensive patient care in Hepatitis C.
  • Further research is needed to elucidate the precise mechanisms linking HCV to oral conditions.

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