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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
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Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Polymorphous light eruption presenting as pinhead papular eruption on the face.

Prescilia Isedeh, Henry W Lim

    Journal of Drugs in Dermatology : JDD
    |November 8, 2013
    PubMed
    Summary

    Polymorphic light eruption (PMLE) is a common sun-induced rash. This study highlights a rare pinpoint papular variant of PMLE affecting the face in African-American males.

    Area of Science:

    • Dermatology
    • Photomedicine
    • Immunodermatology

    Background:

    • Polymorphic light eruption (PMLE) is the most frequent immunologically mediated photodermatosis.
    • It typically affects individuals within their first three decades of life, with a higher incidence in females.
    • Lesions manifest as non-scarring, erythematous, and mildly itchy papules, vesicles, papulovesicles, plaques, or nodules.

    Observation:

    • A specific variant, the pinpoint papular type of PMLE, has been documented in individuals with skin phototypes IV-VI.
    • This variant is characterized by the eruption of 1-2 mm pinpoint papules on sun-exposed skin following ultraviolet radiation exposure.
    • While typically affecting the arms, forearms, hands, and neck, facial involvement is uncommon.

    Findings:

    • This report details two cases of African-American males presenting with the pinpoint papular variant of PMLE.

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  • Notably, these cases involved facial skin, an unusual presentation for this PMLE variant.
  • The findings expand the known clinical spectrum of PMLE in individuals with darker skin types.

    • Implications:

    • This case series broadens the understanding of PMLE presentations, particularly the pinpoint papular variant.
    • It emphasizes the importance of considering PMLE in the differential diagnosis of facial rashes in African-American males, especially after sun exposure.
    • Further research may elucidate specific triggers or genetic factors contributing to this variant's presentation.