Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

2.9K
Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
2.9K
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

52
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
52
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

34
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
34
Skin Cancer01:30

Skin Cancer

5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

30
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
30
Mechanism of Angiogenesis01:10

Mechanism of Angiogenesis

6.4K
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
6.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations between Patterns of Neuroendocrine Liver Metastatic Burden and Outcomes after Liver-Directed Therapy, Systemic Chemotherapy, and Peptide Receptor Radionuclide Therapy.

Neuroendocrinology·2026
Same author

Retronychia in children: A case series.

Pediatric dermatology·2023
Same author

Early propranolol treatment of infantile hemangiomas improves outcome.

Anais brasileiros de dermatologia·2022
Same author

Atopic dermatitis in children and adolescents seen at a general hospital in the City of Buenos Aires.

Archivos argentinos de pediatria·2022
Same author

The Global Reading Room: Treating a Fibrin Sheath.

AJR. American journal of roentgenology·2022
Same author

Closing the Gap in Curative Ablation of Liver Cancer.

Radiology·2021
Same journal

Vesicoureteral reflux in children with urinary tract infections caused by atypical pathogens: Diagnostic accuracy of renal ultrasound.

Archivos argentinos de pediatria·2026
Same journal

The DOHaD concept: Advances and challenges ten years after its inclusion in the pediatric agenda.

Archivos argentinos de pediatria·2026
Same journal

Malnutrition and hypernatremic dehydration as the initial presentation of nephrogenic diabetes insipidus in an infant.

Archivos argentinos de pediatria·2026
Same journal

Biologic therapies in pediatric psoriasis: A single-center experience.

Archivos argentinos de pediatria·2026
Same journal

School violence: An oxymoron.

Archivos argentinos de pediatria·2026
Same journal

Toward a new paradigm in kidney care: An urgent need.

Archivos argentinos de pediatria·2026
See all related articles

Related Experiment Video

Updated: May 6, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

806

[Infantile hemangiomas].

Ana Giachetti, M Magdalena Sojo, Ricardo García-Mónaco

    Archivos Argentinos De Pediatria
    |November 8, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Infantile hemangiomas, common in infants, can lead to serious complications in 10-15% of cases. This review focuses on identifying high-risk hemangiomas needing specialized care and outlines current treatment options.

    More Related Videos

    A Patient-Derived Xenograft Model for Venous Malformation
    06:51

    A Patient-Derived Xenograft Model for Venous Malformation

    Published on: June 15, 2020

    4.5K
    A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay
    08:26

    A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay

    Published on: April 12, 2018

    7.5K

    Related Experiment Videos

    Last Updated: May 6, 2026

    Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
    05:30

    Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

    Published on: August 8, 2025

    806
    A Patient-Derived Xenograft Model for Venous Malformation
    06:51

    A Patient-Derived Xenograft Model for Venous Malformation

    Published on: June 15, 2020

    4.5K
    A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay
    08:26

    A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay

    Published on: April 12, 2018

    7.5K

    Area of Science:

    • Pediatric Oncology
    • Dermatology
    • Vascular Anomalies

    Context:

    • Infantile hemangiomas (IHs) are the most frequent benign tumors in infancy.
    • While typically self-limiting, 10-15% of IHs pose risks for complications.
    • Complications can include functional impairment and permanent cosmetic disfigurement, particularly during the proliferative phase.

    Purpose:

    • To provide an update on the natural history of infantile hemangiomas.
    • To emphasize the identification of IHs requiring specialized diagnostic evaluations and multidisciplinary follow-up.
    • To review current indications for study and treatment modalities for IHs.

    Summary:

    • This review delineates the natural history of infantile hemangiomas (IHs).
    • It highlights the importance of identifying IHs with a high risk of complications.
    • Current diagnostic and therapeutic strategies are discussed.

    Impact:

    • Facilitates early identification of at-risk infantile hemangiomas.
    • Guides multidisciplinary management and closer follow-up for complicated cases.
    • Informs clinical decision-making regarding optimal treatment strategies for infantile hemangiomas.