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Isolated posterior fossa involvement in posterior reversible encephalopathy syndrome
Yukie Shimizu1, Khin Khin Tha, Akihiro Iguchi
1Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital; Kita-ku, Sapporo, Japan - kktha@med.hokudai.ac.jp.
Abstract:
Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible vasogenic edema affecting the subcortical white matter of bilateral occipital and parietal lobes. We describe a case of isolated posterior fossa involvement of PRES which occurred during remission induction chemotherapy for T-cell acute lymphoblastic leukemia. Both the brainstem and cerebellum were extensively involved, but the supratentorial structures were completely spared. The follow-up magnetic resonance images revealed reversibility of most lesions. The knowledge of atypical radiological features of PRES is essential for prompt diagnosis.
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