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Are cataracts associated with osteoporosis?
Arie Y Nemet1, Joel Hanhart, Igor Kaiserman
1Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel.
Clinical Ophthalmology (Auckland, N.Z.)
|November 9, 2013
Summary
Osteoporosis is more common in patients with cataracts, suggesting a link between these conditions. Further research into shared causes like calcium imbalance may reveal new treatment strategies for osteoporosis and cataracts.
Area of Science:
- Gerontology
- Ophthalmology
- Orthopedics
Background:
- Calcium plays a role in osteoporosis and cataract development.
- This study investigates the relationship between osteoporosis and cataracts.
Purpose of the Study:
- To determine the prevalence of osteoporosis in patients undergoing cataract surgery.
- To assess the association between osteoporosis and cataracts.
Main Methods:
- Retrospective observational case-control study.
- Involved 12,984 patients undergoing cataract surgery and 25,968 controls (aged >50).
- Electronic medical records were reviewed to determine osteoporosis prevalence and odds ratios.
Main Results:
- Osteoporosis was more prevalent in cataract patients across all age groups.
- Factors associated with increased osteoporosis risk included age, female sex, higher socioeconomic status, smoking, chronic renal failure, hyperthyroidism, rheumatoid arthritis, inflammatory bowel diseases, and cataracts.
- Obesity was found to be a protective factor against osteoporosis.
Conclusions:
- Osteoporosis is associated with the presence of cataracts, beyond other known risk factors.
- Potential shared pathophysiological mechanisms include calcium imbalance, hormonal abnormalities, and genetic predisposition.
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