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Updated: May 6, 2026

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
Published on: August 16, 2021
[Interest of collapse therapy in pulmonary extensively drug-resistant tuberculosis]
E Haustraete1, K Campbell1, R Magnier1
1Service de pneumologie, CHU Côte-de-Nacre, avenue Côte-de-Nacre, 14033 Caen cedex 05, France.
Abstract:
Extensively drug-resistant (XDR) tuberculosis is rare in France. Treatment of XDR tuberculosis is difficult and therapeutic failures are frequent. Surgery is considered as one of the therapeutic options, but is of little use regarding its high morbi-mortality. We report successful treatment of a XDR tuberculosis case with a 21-month antibiotic regimen followed by a surgical collapse therapy because of persistence of a large cavity. No relapse was observed after five years. Surgery in the XDR tuberculosis treatment is discussed.
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