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Updated: May 6, 2026

Isolation of Primary Mouse Trophoblast Cells and Trophoblast Invasion Assay
Published on: January 8, 2012
Gestational trophoblastic disease
Alampady K P Shanbhogue1, Neeraj Lalwani, Christine O Menias
1Department of Radiology, Beth Israel Medical Center, 16th Street and 1st Avenue, New York, NY 10003, USA.
Abstract:
Imaging plays a crucial role in diagnosis and management of gestational trophoblastic disease. Ultrasonography is the initial investigation of choice for the diagnosis. Pelvic magnetic resonance (MR) imaging is used as a problem-solving tool for assessment of degree of local invasion. Chest radiography is the recommended initial radiographic staging modality, and chest computed tomography is performed if the radiograph is negative. (18)F-Fluorodeoxyglucose positron emission tomography has been shown to be useful in assessing the active or viable sites of metastases, thereby determining the need for tumor resectability in chemoresistant disease.
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