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Updated: May 6, 2026

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Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry
Published on: May 19, 2020
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Detection of CD59 using flow cytometry
1Division of Transplantation Immunology and Mucosal Biology, MRC Centre for Transplantation, King's College London, Guy's Hospital, London, UK.
Methods in Molecular Biology (Clifton, N.J.)
|November 13, 2013
Abstract:
CD59 is the single regulator of the terminal complement pathway. It has been implicated in disease such as Paroxysmal nocturnal hemoglobinuria (PMH) and cancer. Expression of CD59 protects normal and malignant cells from the cytotoxic potential of the complement system. Here we describe a method, which allows for studying its expression on the surface of cells.

