Related Experiment Video
Updated: May 6, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
[Development of substance use disorders can be prevented].
Mauri Marttunen1, Bettina von der Pahlen
1Terveyden ja hyvinvoinnin laitos, mielenterveys ja päihdepalvelut -osasto, Helsingin yliopisto ja HYKS.
Early substance experimentation in adolescence can lead to established drug use habits. Addressing issues like ADHD and behavioral disorders early can prevent future substance use disorders.
Area of Science:
- Adolescent psychology
- Neurodevelopmental disorders
- Substance abuse research
Context:
- Adolescence is a critical period for the initiation of substance experimentation.
- Established drug use patterns often form during teenage years.
- Co-occurring conditions like ADHD and conduct disorders significantly increase substance use disorder risk.
Purpose:
- To highlight the critical window of adolescence for substance use initiation and habit formation.
- To underscore the role of neurodevelopmental and behavioral disorders in predicting substance use disorders.
- To emphasize the importance of early intervention and prevention strategies.
Summary:
- Substance experimentation begins in early adolescence, with habits solidifying throughout teenage years.
- Attention-deficit/hyperactivity disorder (ADHD) and conduct disorders are significant risk factors for developing substance use disorders.
- Effective prevention and treatment of these conditions can mitigate the risk of future substance use disorders.
Impact:
- Early intervention in adolescent substance abuse can prevent the escalation to full-blown disorders.
- Targeting ADHD and behavioral issues in youth may reduce the incidence of adult substance use disorders.
- Informing drug policy, such as alcohol availability, is crucial for adolescent substance abuse prevention.
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08:05A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
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