Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

150
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
150

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Top-Gated P-MOSFET with CVD-Grown WSe<sub>2</sub> Channels via Self-Aligned WO<sub></sub> Conversion for Spacer Doping.

Nano letters·2025
Same author

A point-of-care electrochemical biosensor for the rapid and sensitive detection of biomarkers in murine models with LPS-induced sepsis.

Biosensors & bioelectronics·2024
Same author

Synthesis of Mesoporous Eu<sup>3+</sup>-Doped Zinc/Silicate Phosphors for Highly Selective and Sensitive Detection of Sulfide Ions.

ACS omega·2023
Same author

Effects of surface treatments of bioactive tricalcium silicate-based restorative material on the bond strength to resin composite.

Dental materials : official publication of the Academy of Dental Materials·2023
Same author

Voltage-modulated surface plasmon resonance biosensors integrated with gold nanohole arrays.

Biomedical optics express·2023
Same author

Optimizing the Micro/Mesoporous Structure of Hierarchical Porous Carbon Synthesized from Petroleum Pitch Using the Solvent-Free Method for Ultra-Fast Capacitive Deionization.

ACS omega·2023
Same journal

AI-driven photophysics-aware design of fluorescent probes with applications in α-synuclein biosensing and inhibitor screening.

Biosensors & bioelectronics·2026
Same journal

Three-dimensional helical integration of high-density linear microelectrode arrays and their cross-tissue applications.

Biosensors & bioelectronics·2026
Same journal

Integration of electrochemical sensors in organ-on-a-chip microfluidic platforms: Advances and perspectives.

Biosensors & bioelectronics·2026
Same journal

DNN-PURE: A deep neural network approach to paper-based urea sensing.

Biosensors & bioelectronics·2026
Same journal

Rationally architected MOF-derived Co<sub>3</sub>O<sub>4</sub>@NiMn-LDH hollow heterostructure-based sensor array empowering sensitive detection and discrimination of neurological biomarkers.

Biosensors & bioelectronics·2026
Same journal

Four-in-one multifunctional CoCu-NC@AuPt nanozyme integrated M13 phage-displayed nanobody based multimodal lateral flow immunoassay for bovine lactoferrin detection.

Biosensors & bioelectronics·2026
See all related articles

Related Experiment Video

Updated: May 6, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

24.3K

A filter-like AuNPs@MS SERS substrate for Staphylococcus aureus detection.

Chi-Chang Lin1, Ying-Mei Yang, Pei-Han Liao

  • 1Department of Chemical and Materials Engineering, Tunghai University, Taichung, Taiwan.

Biosensors & Bioelectronics
|November 14, 2013
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel gold nanoparticle-embedded mesoporous silica substrate for rapid and sensitive cell identification. This new SERS substrate significantly enhances signal detection for applications in medical diagnosis and biological research.

Keywords:
Bacteria fingerprintMesoporous silicaNanoparticlesSERS

More Related Videos

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

8.7K
A Tandem Liquid Chromatography&#8211;Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
08:03

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus

Published on: March 28, 2017

9.0K

Related Experiment Videos

Last Updated: May 6, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

24.3K
A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

8.7K
A Tandem Liquid Chromatography&#8211;Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
08:03

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus

Published on: March 28, 2017

9.0K

Area of Science:

  • Nanotechnology
  • Analytical Chemistry
  • Materials Science

Background:

  • Accurate and rapid cell identification is crucial for medical diagnostics, biological research, and environmental monitoring.
  • Current laboratory methods for cell characterization are often time-consuming and require large cell quantities (10^6-10^8 cells).

Purpose of the Study:

  • To develop a highly sensitive, filter-like Surface-Enhanced Raman Spectroscopy (SERS) substrate for rapid cell identification and concentration.
  • To evaluate the performance of gold nanoparticles embedded in mesoporous silica (AuNPs@MS) for SERS applications.

Main Methods:

  • Synthesized a novel AuNPs@MS substrate using a simple one-spot method.
  • Utilized the substrate for filtration and concentration of analytes from aqueous samples.
  • Applied the substrate for Staphylococcus aureus (S. aureus) SERS discrimination and detection.

Main Results:

  • The AuNPs@MS substrate enabled rapid concentration of target cells within seconds with improved SERS spectral reproducibility.
  • AuNPs@MS demonstrated significantly higher signal intensity and more distinguishable peaks compared to Au/Cr-coated substrates.
  • A 900-fold increase in SERS signals was observed for S. aureus detection at 10^6 CFU/mL using AuNPs@MS with 16 wt% AuNPs.

Conclusions:

  • The developed filter-like AuNPs@MS substrate offers a highly sensitive and reproducible platform for rapid cell identification.
  • This SERS substrate shows great potential for improving detection limits and efficiency in various analytical applications.
  • The substrate is suitable for analyzing small sample volumes (microliters).