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Enzymatic "click" ligation: selective cysteine modification in polypeptides enabled by promiscuous glutathione

Chi Zhang1, Alexander M Spokoyny, Yekui Zou

  • 1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, MA 02139 (USA).

Angewandte Chemie (International Ed. in English)
|November 14, 2013
PubMed
Abstract

No abstract available in PubMed .

Keywords:
bioconjugationclick chemistrycysteine arylationenzyme catalysispeptide macrocyclization

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