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Post-LASIK interface fluid syndrome caused by steroid drops.

Mahfouth A Bamashmus1, Mahmoud F Saleh

  • 1Eye Department, Faculty of Medicine and Health Sciences, Sana'a University, Republic of Yemen ; Refractive Unit, Magrabi Eye Hospital, Sana'a, Republic of Yemen.

Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society
|November 15, 2013
PubMed
Summary

Interface fluid syndrome after laser in situ keratomileusis (LASIK) is a rare complication. Prolonged steroid use can cause this condition, mimicking other issues but improving with steroid cessation and glaucoma treatment.

Keywords:
Fluid interfaceHigh intraocular pressureLASIKMyopiaSteroid drops

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Postoperative Complications

Background:

  • Interface fluid syndrome (IFS) is a rare but serious complication following laser in situ keratomileusis (LASIK).
  • Prolonged topical steroid use is a potential risk factor for developing IFS.
  • IFS can present with signs that mimic other conditions like diffuse lamellar keratitis (DLK).

Purpose of the Study:

  • To describe a case series of patients who developed interface fluid syndrome (IFS) after LASIK.
  • To investigate the role of prolonged steroid use in the development of IFS.
  • To report the outcomes of managing IFS by discontinuing steroids and initiating anti-glaucoma therapy.

Main Methods:

  • Retrospective case series of 8 eyes that developed IFS post-LASIK.
  • Clinical presentation, slit-lamp examination findings, and intraocular pressure (IOP) were documented.
  • Treatment involved cessation of topical steroids and initiation of anti-glaucoma medications.

Main Results:

  • All 8 patients developed IFS after prolonged steroid use for presumed diffuse lamellar keratitis (DLK).
  • Clinical signs included corneal haze and a fluid-filled space between the flap and stroma.
  • High intraocular pressure (IOP) was observed in all affected eyes.
  • Discontinuation of steroids and glaucoma treatment led to significant visual improvement.

Conclusions:

  • Prolonged steroid use can precipitate interface fluid syndrome (IFS) in post-LASIK eyes.
  • IFS should be considered in patients presenting with worsening corneal haze and elevated IOP after LASIK, especially with steroid exposure.
  • Management involves steroid withdrawal and appropriate IOP control, leading to favorable visual outcomes.