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Updated: May 6, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Research progress in pathogenesis of IBD: the role of gut flora]
1Department of Physiology and Pathophysiology Peking University Health Science Center, Beijing 100191, China.
Abstract:
Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic inflammatory disorders of the intestine. Both the etiology and the pathogenesis of IBD remain unclear. In recent years, the role of gut flora in IBD has become one of the most concerned issues. International metagenomic projects targeting the gut microbiota greatly promote the exploration of the role of gut flora in IBD. What are the characteristics of gut flora in IBD? How does it interact with host susceptibility? This review will discuss the enteric dysbacteriosis in IBD and show the interaction between gut flora, especially the dominant gut flora, and host susceptibility in IBD.
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