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Updated: May 5, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
[The links between research and practice: knowledge transfer, the use of evidence-based data and the renewal of
Hélène Lefebvre1, Odette Roy, Sarah Sahtali
1Faculté des sciences infirmières, Université de Montréal, Québec, Canada. helene.lefebvre@umontreal.ca
Abstract:
Nurses in clinical settings still do not fully rely on scientific knowledge to guide their practices and only rarely resort to the literature to find answers to their questions or clinical concerns. The sustainable implementation of projects that use knowledge founded on scientific evidence presents an important challenge that nursing research must address. The goal of this article is to present a strategy adopted by the Réseau infirmier et partenaires de soins (RI-PS) of the Université de Montréal (Québec). The strategy's aim is to promote the optimal and perennial use of scientific knowledge in clinical settings and to incorporate the use of best practices based on scientific evidence to their operating procedure. First, we will present a brief overview of the evolution of nursing research and its impacts, followed by an inventory of the success factors of the use of scientific knowledge in practical settings, and finally the presentation of a model, Implementation Science, on which the RI-PS strategy relies for its projects. We also outline the network and one of its developments, the knowledge transfer portal and healthcare partners (PES).
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