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Updated: May 5, 2026

Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
Probiotics for childhood functional gastrointestinal disorders: a systematic review and meta-analysis
Judith J Korterink1, Lize Ockeloen, Marc A Benninga
1Department of Pediatrics, Jeroen Bosch Hospital, 's Hertogenbosch, The Netherlands.
Unlabelled:
A systematic review and meta-analysis were performed to investigate the quantity and quality of the current evidence regarding the effect of different probiotic strains in the treatment of functional gastrointestinal disorders (FGID) in children and adolescents.
Conclusion:
Probiotics are more effective than placebo in the treatment of patients with abdominal pain-related FGID, especially with respect to patients with irritable bowel syndrome. To date, however, probiotics have not proved effective for children with functional constipation.
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