Related Experiment Video
Updated: May 5, 2026

09:25
Bioluminescent Orthotopic Model of Pancreatic Cancer Progression
Published on: June 28, 2013
26.1K
Lung cancer in Victoria: are we making progress?
Paul L R Mitchell1, Vicky J Thursfield, David L Ball
1Olivia Newton-John Cancer and Wellness Centre, Austin Health, Melbourne, VIC, Australia. paul.mitchell@austin.org.au.
The Medical Journal of Australia
|November 19, 2013
Summary
Improving lung cancer patient management is crucial. Multidisciplinary meetings (MDMs) improve treatment and survival, but early detection and adjuvant chemotherapy use need enhancement.
Area of Science:
- Oncology
- Public Health
- Cancer Research
Background:
- Lung cancer is Australia's leading cause of cancer mortality.
- Effective patient management strategies are essential to improve outcomes.
Purpose of the Study:
- To identify areas for improvement in lung cancer patient management.
- To analyze trends in lung cancer diagnosis and treatment over a decade.
Main Methods:
- Retrospective survey of lung cancer cases reported to the Victorian Cancer Registry (2003-2008).
- Analysis of patient demographics, disease characteristics, investigations, staging, treatment, and survival.
- Comparison with data from a similar survey conducted 10 years prior.
Main Results:
- 841 lung cancer patients were analyzed. Multidisciplinary meeting (MDM) discussion was linked to increased anticancer treatment and improved survival.
- Despite advances, 10% lacked pathological diagnosis and 26% received no anticancer treatment.
- Adjuvant chemotherapy use post-surgery was low (6.9% for R0 resection in NSCLC).
Conclusions:
- Key areas for improvement include increasing pathological diagnosis rates and enhancing the use of postsurgical adjuvant chemotherapy.
- Underuse of chemotherapy and radiotherapy necessitates better treatment protocols.
- Increasing MDM participation is critical for better patient outcomes, alongside strategies for earlier disease detection.
Related Concept Videos
Cancer Vaccines
1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K
Cancer Survival Analysis
870
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
870
Targeted Cancer Therapies
7.1K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.1K
Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
Cancer Prevention
6.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.5K
Treatment Resistant Cancers
2.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
2.7K