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Effect of refractive correction on ocular optical quality measurement using double-pass system
Xiu-Hua Wan1, Xiao-Gu Cai, Li-Ya Qiao
1Beijing Institute of Ophthalmology, Beijing 100730, China; Beijing Tongren Eye Center, Beijing 100730, China; Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology & Visual Science Key Laboratory, Beijing 100730, China.
Chinese Medical Journal
|November 19, 2013
Summary
The Optical Quality Analysis System II (OQAS) is reliable for measuring ocular optical quality. However, caution is advised when using its built-in optometer for high myopia patients.
Area of Science:
- Ophthalmology
- Optometry
- Vision Science
Background:
- The Optical Quality Analysis System II (OQAS) is the sole commercial device employing the double-pass (DP) technique for objective ocular retinal image quality assessment.
- Evaluating the influence of spectacle lenses on ocular optical quality parameters and validating the OQAS optometer are crucial for clinical application.
Purpose of the Study:
- To assess the impact of spectacle lenses on ocular optical quality parameters.
- To validate the accuracy and reliability of the OQAS built-in optometer compared to subjective refraction.
Main Methods:
- Seventy eyes of healthy volunteers underwent optical quality measurements using OQAS with a 4.0 mm artificial pupil.
- Measurements were taken with spectacle correction (subjective refraction) and the OQAS built-in optometer.
- Analyzed parameters included modulation transfer function cutoff frequency, Strehl ratio, and point spread function (PSF) widths (PSF10, PSF50).
Main Results:
- No significant differences were observed in optical quality parameters between spectacle and optometer corrections (P > 0.05).
- Good agreement and intraobserver repeatability were found for both correction methods.
- Best focus difference was the primary factor associated with optical quality parameter variations; high myopia patients showed better optical quality with spectacle correction.
Conclusions:
- The OQAS, utilizing the DP system, is a clinically reliable instrument for objective ocular optical quality measurement.
- Measurements obtained with the OQAS built-in optometer in high myopia patients require careful interpretation due to potential biases.

