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Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Published on: February 20, 2015

Securing poultry production from the ever-present Eimeria challenge.

Damer P Blake¹, Fiona M Tomley¹

¹Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, UK.

Trends in Parasitology

|November 19, 2013

Summary

This summary is machine-generated.

Coccidiosis, an intestinal disease in livestock caused by Eimeria parasites, significantly impacts poultry production. This review explores new methods for developing cost-effective vaccines against Eimeria to improve animal health and food security.

Keywords:

chickens coccidiosis food security new approaches vaccines

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Area of Science:

Veterinary Parasitology
Poultry Health
Vaccine Development

Background:

Coccidiosis, caused by Eimeria protozoan parasites, is a major global livestock disease, particularly affecting the poultry industry.
High-density housing in poultry farming facilitates parasite transmission, leading to significant economic losses.
Current control methods include husbandry, anticoccidial drugs, and live vaccines, but drug resistance and persistent infections remain challenges.

Purpose of the Study:

To review recent advancements in the production of third-generation coccidiosis vaccines for poultry.
To highlight methods for identifying immunoprotective antigens and utilizing transgenic Eimeria for vaccine development.
To address the need for cheaper and more effective coccidiosis vaccines to combat drug resistance and improve food security.

Main Methods:

Review of recent scientific literature on Eimeria vaccine development.
Focus on robust methods for identifying immunoprotective antigens.
Exploration of the use of transgenic Eimeria in vaccine production.

Main Results:

Identification of promising immunoprotective antigens from Eimeria species.
Development of strategies for producing more affordable third-generation vaccines.
Potential for transgenic Eimeria to serve as effective vaccine candidates.

Conclusions:

Advancements in antigen identification and transgenic technology offer new avenues for cost-effective coccidiosis vaccine production.
Improved vaccines are crucial for overcoming drug resistance and mitigating the impact of coccidiosis on poultry productivity and global food security.
Further research into these novel approaches is warranted to ensure widespread availability and efficacy.