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Updated: May 5, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Hypodermal metastasis of malignant melanoma to the cheek
A Moya-Plana1, C Robert2, O Laccourreye3
1Faculté de médecine Paris-Descartes, université Paris Descartes Sorbonne Paris Cité, service d'ORL et de chirurgie cervico-faciale, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France; Service d'ORL et de chirurgie cervico-faciale, institut Gustave-Roussy, 114, rue Edouard-Vaillant, 94805 Villejuif, France.
Introduction:
On the basis of a case of hypodermal metastasis of malignant melanoma to the cheek and a review of the literature, we analyze treatment and recent progress in metastatic malignant melanoma.
Case-Report:
A 55-year-old woman presented with a facial hypodermal metastasis of a slow-growing melanoma of the ankle that had been treated by surgery.
Discussion/Conclusion:
Metastatic malignant melanoma treatment, which was usually palliative when surgical resection was not feasible, has been improved by innovations in immunotherapy (ipilimumab) and targeted therapy (vemurafenib). Genetic profiling is an interesting line of research to improve short-term prognosis in these tumors.
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