Related Experiment Video
Updated: May 5, 2026

08:57
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
3.1K
MR imaging features of spindle cell lipoma
Anand Kirwadi1, Rehan Abdul-Halim, Malee Fernando
1Radiology Department, Sheffield Teaching Hospitals NHS Trust, Herries Road, Sheffield, S5 7AU, UK, anand.kirwadi@doctors.org.
Skeletal Radiology
|November 19, 2013
Summary
Spindle cell lipomas (SCL) show varied internal signal patterns on MR imaging, with low fat content lesions appearing as commonly as intermediate and high fat content ones. Histopathology confirms the MR imaging fat:non-fat signal pattern accurately.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Spindle cell lipomas (SCL) are rare benign soft tissue tumors.
- Accurate MR imaging assessment is crucial for diagnosis and differentiating SCL from other lipomatous lesions.
Purpose of the Study:
- To evaluate the MR imaging characteristics of SCL.
- To correlate MR imaging findings with histopathological features.
Main Methods:
- Retrospective review of 25 histologically confirmed SCL cases.
- Analysis of MR imaging features including fat signal content, fat suppression, and contrast enhancement.
- Comparison of imaging findings with histopathological grading of fat and non-adipose tissue.
Main Results:
- SCLs predominantly occurred in middle-aged males on the upper back, shoulder, or neck.
- MR imaging revealed a broad spectrum of fat signal content, with low, intermediate, and high fat content lesions observed.
- Septal/nodular enhancement was a common finding, and core needle biopsy provided definitive diagnosis in all cases.
Conclusions:
- MR imaging demonstrates diverse internal signal patterns in SCL, with varying fat content.
- The MR imaging assessment of fat to non-fat composition in SCL correlates well with histopathological findings.

