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Updated: May 5, 2026
High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012
Motion-compensated compressed sensing for dynamic contrast-enhanced MRI using regional spatiotemporal sparsity and
Xiao Chen1, Michael Salerno, Yang Yang
1Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Purpose:
Dynamic contrast-enhanced MRI of the heart is well-suited for acceleration with compressed sensing (CS) due to its spatiotemporal sparsity; however, respiratory motion can degrade sparsity and lead to image artifacts. We sought to develop a motion-compensated CS method for this application.
Methods:
A new method, Block LOw-rank Sparsity with Motion-guidance (BLOSM), was developed to accelerate first-pass cardiac MRI, even in the presence of respiratory motion. This method divides the images into regions, tracks the regions through time, and applies matrix low-rank sparsity to the tracked regions. BLOSM was evaluated using computer simulations and first-pass cardiac datasets from human subjects. Using rate-4 undersampling, BLOSM was compared with other CS methods such as k-t SLR that uses matrix low-rank sparsity applied to the whole image dataset, with and without motion tracking, and to k-t FOCUSS with motion estimation and compensation that uses spatial and temporal-frequency sparsity.
Results:
BLOSM was qualitatively shown to reduce respiratory artifact compared with other methods. Quantitatively, using root mean squared error and the structural similarity index, BLOSM was superior to other methods.
Conclusion:
BLOSM, which exploits regional low-rank structure and uses region tracking for motion compensation, provides improved image quality for CS-accelerated first-pass cardiac MRI.
