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Updated: Feb 26, 2026

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A New Straightforward Method for Lipophilicity logP Measurement using 19F NMR Spectroscopy
Published on: January 30, 2019
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[Flow analysis by phase modulation of NMR signals]
Archives Internationales De Physiologie Et De Biochimie
|December 1, 1985
Summary
This study introduces time-modulated field-gradient sequences for Nuclear Magnetic Resonance (NMR) imaging. The method effectively distinguishes between stationary and mobile protons, offering sensitivity to flow direction.
Area of Science:
- Physics
- Biomedical Engineering
- Medical Imaging
Context:
- Nuclear Magnetic Resonance (NMR) signal processing
- Flow velocity measurement in biological systems
- Magnetic Resonance Imaging (MRI) techniques
Purpose:
- To develop novel time-modulated field-gradient sequences for NMR.
- To enable selective phase encoding of spatial location or flow velocity.
- To discriminate between stationary and mobile protons based on phase modulation.
Summary:
- The described method utilizes time-modulated field-gradient sequences in NMR.
- These sequences selectively encode spatial location or flow velocity.
- A key feature is the phase modulation that differentiates stationary from mobile protons, offering directional sensitivity and independence from relaxation times.
Impact:
- Enhances the capability of NMR to quantify fluid dynamics.
- Provides a new tool for non-invasive flow measurement in various applications.
- Improves the specificity and robustness of NMR-based flow imaging.
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