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MAGE-A3-specific anticancer immunotherapy in the clinical practice

Vincent G Brichard1, Quentin Godechal

  • 1GlaxoSmithKline Biologicals; Rixensart, Belgium.

Oncoimmunology
|November 19, 2013
PubMed

Antigen-specific immunotherapy may offer a unique approach to fight cancer. We have demonstrated that specific immunotherapeutic regimens involving recombinant melanoma antigen family A3 (MAGE-A3) and different immunostimulants exert clinical anticancer activity. In particular, the combination of recombinant MAGE-A3 and AS15, a multicomponent immunostimulant, was found to elicit robust antigen-specific immune responses.

Keywords:
MAGE-A3biomarkerscancerimmunizationimmunotherapy

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