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Updated: May 5, 2026

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
Published on: November 12, 2019
Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
1Department of Pediatric Hematology and Oncology; University Children's Hospital Muenster; Muenster, Germany.
Abstract:
The adoptive transfer of T cells expressing chimeric antigen receptors (CARs) has emerged as a promising immunotherapeutic strategy against cancer. Administering CAR-expressing T cells in combination with agents that promote the expression of CAR targets or optimize T-cell function within the tumor microenvironment may further improve the therapeutic potential of this approach.
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