[Growth and body composition changes in late preterm infants in the first months of life]

N Liotto1, F Garbarino, E Garavaglia

  • 1Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS "Ca' Granda" Ospedale Maggiore Policlinico, University of Milan, Via Commenda 12, 20122 Milan, Italy. nadia.liotto@unimi.it

Insights

Late preterm infants show rapid fat mass gain, reaching levels similar to very low birth weight infants by 3 months corrected age. This catch-up fat may influence future chronic disease risk.

Area of Science:

  • Neonatal physiology and growth
  • Pediatric nutrition and body composition

Context:

  • Late preterm infants (34-36 weeks gestation) have distinct growth trajectories compared to extremely preterm and full-term infants.
  • Understanding early body composition is crucial for assessing long-term health outcomes in preterm populations.

Purpose:

  • To compare the growth and body composition of late preterm infants with extremely preterm and full-term infants.
  • To analyze anthropometric parameters and body composition changes from birth to 3 months corrected age.

Summary:

  • Late preterm infants exhibited higher weight, length, and head circumference than very low birth weight infants but lower fat mass early on.
  • A rapid increase in fat mass was observed in late preterm infants between the fifth day of life and term corrected age, reaching levels comparable to very low birth weight infants by 3 months corrected age.
  • Preterm infants showed higher fat mass percentage in the first month corrected age compared to full-term infants, a difference that diminished by 3 months corrected age.

Impact:

  • Findings highlight the dynamic nature of body composition changes in late preterm infants.
  • The rapid fat accumulation warrants further investigation into its potential long-term health implications, including the risk of chronic diseases.
Abstract

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