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Updated: May 5, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
[Some important aspects about treatment of open globe injury]
1Department of Ophthalmology of Peking University Third Hospital, Beijing 100191, China.
Abstract:
Open globe injury is a common cause for blindness. Injured eyes with no light perception (NLP) should not be enucleated before exploratory vitrectomy. Some NLP eyes may attain light perception or better vision through the vitrectomy. The decision of enucleation should be determined during exploratory vitrectomy. The timing of vitrectomy in the open globe injury still has controversy, but more surgeons agreed that vitrectomy should be performed within 2 weeks after open globe injury. The deadline of timing of vitrectomy is 4 weeks after injury. Retinectomy around the edge of the wound and retinal re-attachment surgery are the key points to prevent proliferative vitreoretinopathy resulted from the injury.
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