Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

5.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
5.2K
Computed Tomography01:10

Computed Tomography

7.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.6K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

902
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
902
The Thyroid Gland01:23

The Thyroid Gland

7.0K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.0K
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

976
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
976

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigation of the impact of D, L-methadone on ALA-PDT in multiple glioblastoma cell lines.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2026
Same author

Investigations on MRI changes after 5-aminolevulinic acid mediated interstitial photodynamic therapy for malignant gliomas.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2025
Same author

Second-Generation Wide-Field Visualization Devices for 5-ALA-Induced Fluorescence and Concepts for Validation in Neurosurgery-A Systematic Review.

Neurosurgery practice·2025
Same author

Persistent desmoglein-1 downregulation and periostin accumulation in histologic remission of eosinophilic esophagitis.

The Journal of allergy and clinical immunology·2024
Same author

Simple Characterization of Cylindrical Diffuser Fibers With a Fluorescent Layer.

Lasers in surgery and medicine·2024
Same author

Influence of vitamins and food on the fluorescence spectrum of human urine.

Lasers in surgery and medicine·2024

Related Experiment Video

Updated: May 5, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.8K

Optical coherence tomography as a method to identify parathyroid glands.

Roland Ladurner1, Klaus K J Hallfeldt, Norah Al Arabi

  • 1Department of Surgery, Ludwig Maximilians University Munich, Innenstadt Medical Campus, Nussbaumstrasse 20, 80336, Munich, Germany.

Lasers in Surgery and Medicine
|November 20, 2013
PubMed
Summary

Optical coherence tomography (OCT) shows high sensitivity in differentiating parathyroid tissue from thyroid, lymph node, and adipose tissues. Further intraoperative studies are recommended to confirm these ex vivo findings.

Keywords:
OCTparathyroid glandparathyroid surgery

More Related Videos

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification
08:07

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification

Published on: August 1, 2025

1.2K
Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

7.1K

Related Experiment Videos

Last Updated: May 5, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.8K
Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification
08:07

Procurement of Parathyroid Glands from Living Donor Pigs and Ex Vivo Identification

Published on: August 1, 2025

1.2K
Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

7.1K

Area of Science:

  • Surgical anatomy
  • Medical imaging technology
  • Histopathology

Background:

  • Accurate identification of parathyroid glands is crucial during parathyroid surgery.
  • Distinguishing parathyroid tissue from surrounding structures like thyroid, lymph nodes, and fat can be challenging.

Purpose of the Study:

  • To assess the feasibility of using optical coherence tomography (OCT) for distinguishing parathyroid tissue from other tissues.
  • To evaluate OCT's accuracy in differentiating parathyroid glands, thyroid tissue, lymph nodes, and adipose tissue.

Main Methods:

  • Ex vivo OCT images and histological sections were obtained from parathyroid glands, thyroid tissue, lymph nodes, and fat.
  • Two blinded investigators evaluated OCT images, comparing them to corresponding histology.
  • Sensitivity, specificity, and interobserver agreement (κ coefficient) were calculated.

Main Results:

  • OCT demonstrated high sensitivity (84%) and specificity (94%) in distinguishing parathyroid tissue from other entities.
  • Substantial interobserver agreement (κ=0.97) was observed between the two investigators.
  • 320 OCT images from 32 patients were analyzed.

Conclusions:

  • Optical coherence tomography (OCT) is a highly sensitive tool for differentiating parathyroid tissue from thyroid, lymph nodes, and adipose tissue.
  • Ex vivo results suggest OCT's potential utility in surgical settings.
  • Further intraoperative validation of OCT imaging is warranted.