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Related Concept Videos

DNA Bacteriophages01:26

DNA Bacteriophages

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Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
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Viral Replication: Lysogenic Cycle01:16

Viral Replication: Lysogenic Cycle

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The lysogenic cycle is a crucial viral replication strategy that allows bacteriophages to persist within host cells without immediately destroying them. This process is primarily observed in temperate phages, such as bacteriophage lambda (λ), which infects Escherichia coli. The cycle allows the viral genome to persist across bacterial generations while keeping host cells viable.Integration of the Viral GenomeUpon infection, bacteriophage lambda attaches to the bacterial surface and injects...
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Viral Replication: Lytic Cycle01:20

Viral Replication: Lytic Cycle

1.1K
Bacteriophages, or phages, are viruses that specifically infect bacteria. Among them, T-even bacteriophages, such as T4, exhibit a well-characterized lytic replication cycle in Escherichia coli (E. coli). This process ensures the rapid proliferation of the virus while ultimately leading to the destruction of the bacterial host.Attachment and DNA InjectionThe infection process begins with the recognition and binding of the T4 phage to the E. coli cell surface. Tail fibers of the phage...
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Lytic Cycle of Bacteriophages01:30

Lytic Cycle of Bacteriophages

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Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the...
77.2K
Lysogenic Cycle of Bacteriophages00:43

Lysogenic Cycle of Bacteriophages

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In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
67.2K
CRISPR and crRNAs02:53

CRISPR and crRNAs

18.6K
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
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Updated: Jan 1, 2026

Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics
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Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics

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Listeria phages: Genomes, evolution, and application.

Jochen Klumpp1, Martin J Loessner

  • 1Institute of Food, Nutrition and Health; ETH Zurich; Zurich, Switzerland.

Bacteriophage
|November 20, 2013
PubMed
Summary
This summary is machine-generated.

Listeria bacteriophages are crucial for understanding foodborne illness. This overview details their genomics, host interactions, and applications in diagnostics and biotechnology.

Keywords:
CRISPRMosaic genomesbiocontrolcomKendolysinhomologous recombinationpathogen detectionreporter phage

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Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
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Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
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Area of Science:

  • Microbiology
  • Genomics
  • Food Safety

Background:

  • Listeria is a significant foodborne pathogen causing potentially fatal Listeriosis.
  • Hundreds of Listeria bacteriophages are known, but detailed characterization and genome sequencing are limited.
  • Understanding these phages is vital for food safety and public health.

Approach:

  • Comprehensive review of existing literature on Listeria bacteriophage genomics.
  • Analysis of the role of bacteriophages in Listeria host evolution and pathogenicity.
  • Exploration of current and potential applications in biotechnology and diagnostics.

Key Points:

  • Limited genomic data available for most characterized Listeria bacteriophages.
  • Bacteriophages play a role in the evolution and pathogenicity of Listeria.
  • Diverse applications exist for Listeria phages in diagnostics and biotechnology.

Conclusions:

  • Further genomic characterization of Listeria bacteriophages is needed.
  • Listeria bacteriophages offer promising avenues for food safety interventions and diagnostics.
  • Continued research will enhance our understanding and utilization of these phages.