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Low dose liraglutide in Indian patients with type 2 diabetes in the real world setting
Debmalya Sanyal1, Anirban Majumdar
1Department of Endocrinology, KPC Medical College, Kolkata, West Bengal, India ; Department of Endocrinology, RTIICS, Kolkata, West Bengal, India.
Abstract:
Liraglutide, a human glucagon-like peptide-1 receptor agonist, decreases glycosylated hemoglobin and causes weight loss. However, the cost of therapy and gastrointestinal side- effects such as nausea and diarrhea are important impediments to adherence and long-term compliance. We assessed the efficacy, safety and tolerability of low dose (0.6 mg) liraglutide in obese uncontrolled longstanding type 2 diabetes in Indian patients. Low dose liraglutide improved glycemic control and decreased weight. However, there was a significant drop out because of gastrointestinal intolerance and financial constraints.
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