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Prenylation and methylation reactions in phylloquinone (vitamin K1) synthesis in Capsicum annuum plastids
J P Gaudillière1, A d'Harlingue, B Camara
1Laboratoire de Régulations Métaboliques et Différenciation des Plastes, Tour 53, 2ème étage, Université Pierre et Marie Curie (Paris 6), 4 place Jussieu, F-75230, Paris Cédex 05, France.
Abstract:
The biosynthesis of phylloquinone (vitamin K1) was examined using Capsicum fruit chloroplasts and chromoplasts (apparently phylloquinone free). In both cases, the synthesis of phylloquinone from α-naphthoquinone, dihydro-α-naphthoquinone, 1,4-dihydroxy-2-naphthoic acid (as precursors of the ring moiety) and (S)-adenosyl-L-methionine was achieved. In the presence of phytylpyrophosphate, the biosynthesis of phylloquinone in both organelles is particularly enhanced when 1,4-dihydroxy-2-naphthoic acid is used.
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