Giant cystic intraventricular cerebral cavernous malformation: MRI with pathologic correlation. A case report

Area of Science:

• Neurology
• Radiology
• Pathology

Background:

• Cerebral cavernous malformations (CCMs) are vascular malformations in the brain.
• Giant CCMs, particularly cystic variants within the ventricles, are uncommon.
• Previous cranial irradiation may influence the development of vascular lesions.

Purpose of the Study:

• To document an unusual case of a giant cystic cerebral cavernous malformation.
• To illustrate the magnetic resonance imaging (MRI) and histological findings of this rare entity.
• To emphasize the importance of including giant cystic CCMs in the differential diagnosis of intraventricular lesions.

Main Methods:

• Case presentation of a 26-year-old male with a giant cystic CCM.
• Review of MRI findings characterizing the lesion.
• Analysis of histological features post-excision (implied).

Main Results:

• A single, giant ( >6 cm) cystic CCM was identified in the left lateral ventricle.
• The patient had a history of cranial irradiation in childhood.
• The lesion presented as an intraventricular hemorrhagic cystic abnormality.

Conclusions:

• Giant cystic CCMs represent a rare but important differential diagnosis for intraventricular cystic lesions.
• Radiological and pathological features are crucial for accurate diagnosis.
• Awareness of the spectrum of CCMs is essential for effective patient management.