Related Experiment Video
Updated: Feb 8, 2026

09:55
Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases
Published on: January 5, 2024
1.9K
A novel compound 6D-offset simulating phantom and quality assurance program for stereotactic image-guided radiation
Dennis Yuen Kan Ngar1, Michael Lok-Man Cheung, Michael Koon-Ming Kam
1The Chinese University of Hong Kong. dykngar@hotmail.com.
Journal of Applied Clinical Medical Physics
|November 22, 2013
Summary
A new quality assurance system was developed for 6D image-guided radiation therapy (IGRT) systems. This system effectively validated the BrainLAB IGRT system, ensuring precision for stereotactic radiotherapy and overall system integrity.
Area of Science:
- Medical Physics
- Radiation Oncology
- Quality Assurance
Background:
- Image-guided radiation therapy (IGRT) systems are crucial for precise radiation delivery.
- Commissioning and routine testing of 6D IGRT systems require robust quality assurance (QA) methods.
- Existing QA protocols may not fully address the complexities of 6D IGRT systems.
Purpose of the Study:
- To develop and evaluate a comprehensive QA device and program for commissioning and routine testing of 6D IGRT systems.
- To assess the performance of a BrainLAB ExacTrac X-ray IGRT system integrated with a Varian Clinac.
- To establish system characteristics and validate the precision of the 6D IGRT system for stereotactic radiotherapy.
Main Methods:
- Development and fabrication of a novel compound 6D-offset simulating phantom.
- Implementation of a QA program generating random 6D offset values for phantom setup and shifts.
- Automated detection and correction of phantom offsets by the BrainLAB IGRT system via a robotic couch.
- Analysis of detection errors, correction errors, and their correlations from routine QA data.
Main Results:
- The 6D IGRT system demonstrated high precision, with component detection and correction errors within ±1 mm and ±1°.
- Translational and rotational resultant errors were found to be 0.50 ± 0.27 mm and 0.54 ± 0.23°, respectively.
- Individual component errors were largely independent of their initial offset values, indicating system stability.
Conclusions:
- The developed QA methodology is competent in assuring the overall integrity of 6D IGRT systems.
- The BrainLAB 6D IGRT system, when added to a standard linear accelerator, is sufficiently precise for stereotactic radiotherapy.
- Annual comprehensive analyses are recommended for maintaining local system consistency and enabling external cross-comparison. A 1.5 mm 3D margin from CTV to PTV is confirmed for this IGRT system.
More Related Videos
Related Concept Videos
Quality Assurance
2.4K
Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
2.4K
Biological Effects of Radiation
18.0K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.0K
Radiation: Applications
1.8K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
The average...
1.8K
Molecules and Compounds
68.9K
Atoms and Molecules
68.9K
Organic Compounds
57.5K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
57.5K
Absorption of Radiation
1.3K
The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
1.3K

