Related Experiment Video
Updated: May 5, 2026
A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
Seasonal influenza vaccination coverage - United States, 2009-10 and 2010-11
Insights
Annual influenza vaccination is crucial for preventing severe illness and death. This strategy is most effective in protecting vulnerable populations, including young children and the elderly, from influenza virus complications.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Influenza virus infections cause significant global morbidity and mortality across all age groups.
- While children under 5 have the highest infection rates, the elderly, very young children, and individuals with medical conditions face the highest hospitalization and death rates.
- Influenza complications lead to over 226,000 hospitalizations annually in the US, with estimated deaths ranging from 3,000 to 49,000 between 1976-2006.
Purpose of the Study:
- To highlight the severe impact of influenza virus infections.
- To identify high-risk populations for influenza-related complications.
- To emphasize the importance of vaccination as a preventive measure.
Main Methods:
- This study is a review of existing data on influenza infection, hospitalization, and mortality rates.
- Analysis of epidemiological data from 1976-2006 in the United States.
- Synthesis of information on the effectiveness of influenza vaccination.
Main Results:
- Influenza virus infections lead to substantial illness and fatalities.
- Elderly individuals, children under 2, and those with underlying health issues are most susceptible to severe outcomes.
- Annual influenza vaccination is identified as the most effective method for preventing influenza and its complications.
Conclusions:
- Influenza virus poses a significant public health threat, necessitating effective preventive strategies.
- Vaccination remains the primary and most effective tool for mitigating influenza's impact.
- Protecting vulnerable populations through vaccination is essential for reducing disease burden.
Abstract:
Infection with influenza viruses can cause severe morbidity and mortality among all age groups. Children, particularly those aged <5 years, have the highest incidence of infection during epidemic periods; however, the highest rates of influenza-associated hospitalizations and deaths are among the elderly (aged ≥65 years), children aged <2 years, and those of any age with underlying medical conditions. Each year, influenza-related complications are estimated to result in more than 226,000 hospitalizations. During 1976-2006, estimates of influenza-associated deaths in the United States ranged from approximately 3,000 to an estimated 49,000 persons. Annual vaccination is the most effective strategy for preventing influenza virus infection and its complications.
Related Concept Videos
01:27Influenza
01:51Vaccinations
01:28Infectious Diseases and Their Occurrence
01:21Vaccines