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Updated: May 5, 2026
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Bacteriophage Effectiveness for Biocontrol of Foodborne Pathogens Evaluated via High-Throughput Settings
Published on: August 19, 2021
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Emerging biomedicines based on bacteriophages.
Jianlong Yan1, Xiangyu Fan, Jianping Xie
1Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, School of Life Sciences, Southwest University, Beibei, Chongqing 400715, China.
Critical Reviews in Eukaryotic Gene Expression
|November 26, 2013
Summary
Bacteriophages, bacterial viruses, show promise as therapeutics against antibiotic resistance. They also offer new avenues for drug delivery and diagnostics through engineered systems.
Area of Science:
- Microbiology
- Virology
- Biotechnology
Background:
- Bacteriophages are ubiquitous bacterial viruses with potential therapeutic applications.
- Antibiotic resistance is a growing global health concern.
- Bacteriophage-derived proteins like endolysins and holins are being explored for antimicrobial properties.
Purpose of the Study:
- To explore the therapeutic potential of bacteriophages and their components against antibiotic-resistant bacteria.
- To investigate bacteriophage-based systems for drug delivery.
- To examine the use of engineered bacteriophages in diagnostic methods.
Main Methods:
- Review of existing literature on bacteriophage applications.
- Analysis of bacteriophage-encoded proteins (endolysins, holins) for antimicrobial activity.
- Exploration of bacteriophage-based delivery systems and diagnostic platforms.
Main Results:
- Bacteriophages and their proteins demonstrate significant potential as alternatives to conventional antibiotics.
- Bacteriophage-derived systems show promise for targeted drug delivery.
- Engineered bacteriophages offer novel approaches for diagnostic applications.
Conclusions:
- Bacteriophages represent a versatile platform for addressing antibiotic resistance.
- Further research into bacteriophage-based therapeutics, drug delivery, and diagnostics is warranted.
- Bacteriophages are emerging as key players in modern medicine and biotechnology.
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