Molecular diagnostics in the neoplasms of the pancreas, liver, gall bladder, and extrahepatic biliary tract
Related Experiment Video For Extrahepatic biliary tract
Updated: May 5, 2026
Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines
Published on: October 8, 2015
Michael Weindel1, Muhammad Zulfiqar, Amarpreet Bhalla
1Department of Pathology, Detroit Medical Center, Karmanos Cancer Center, Wayne State University School of Medicine, 540 East Canfield, Detroit, MI 48201, USA.
Abstract:
Pancreatic neoplasms, including ductal adenocarcinoma, intraductal papillary mucinous neoplasm, solid pseudopapillary neoplasm, pancreatic endocrine neoplasms, acinar cell carcinoma, and ampullary carcinoma, are associated with different genetic abnormalities. Liver neoplasms, including hepatic adenomas, hepatocellular carcinomas, and cholangiocarcinomas, are associated with identifiable risk factors and genetic changes. Gall bladder adenomas and adenocarcinomas arise from distinct molecular pathways. The molecular abnormalities seen in these tumors are not used routinely in the molecular diagnostic laboratory.
