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Psychiatric disorders in persistent and remitted Sydenham's chorea
Janaina Moreira1, Arthur Kummer1, Estefânia Harsányi1
1Neuropsychiatric Branch, Neurology Unit, University Hospital, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Parkinsonism & Related Disorders
|November 26, 2013
Summary
Psychiatric disorders are common in Sydenham's chorea (SC) patients. The study found no significant difference in psychiatric conditions between SC patients in remission and those with persistent symptoms, except for depression.
Area of Science:
- Neurology
- Psychiatry
- Pediatric Neurology
Background:
- Sydenham's chorea (SC) is linked to a higher incidence of psychiatric disorders.
- Understanding the prevalence of psychiatric conditions in SC patients is crucial for comprehensive care.
Purpose of the Study:
- To investigate the frequency of psychiatric disorders in Sydenham's chorea patients.
- To compare psychiatric disorder rates between SC patients in remission and those with active chorea.
Main Methods:
- A cohort of 50 Sydenham's chorea patients underwent detailed psychiatric evaluations.
- Patients were assessed for various psychiatric disorders, including depression, anxiety, social phobia, and OCD.
Main Results:
- Major depression, generalized anxiety disorder, social phobia, and obsessive-compulsive disorder were the most prevalent psychiatric disorders.
- Overall psychiatric disorder frequency did not differ between SC patients in remission and those with persistent chorea.
- Depressive disorders were significantly more frequent in SC patients with persistent chorea.
Conclusions:
- Psychiatric disorders are a common comorbidity in young adults with Sydenham's chorea.
- The presence of psychiatric disorders in SC patients is independent of the motor symptom status, with the exception of depression.
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