Related Experiment Video
Updated: May 5, 2026
09:16
Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
Published on: February 16, 2017
18.2K
Classical conditioning and pain: conditioned analgesia and hyperalgesia
Gonzalo Miguez1, Mario A Laborda2, Ralph R Miller1
1State University of New York at Binghamton, USA.
Acta Psychologica
|November 26, 2013
Summary
Associative learning can alter pain responses. Cues linked to stress can cause pain relief (analgesia) or increased pain sensitivity (hyperalgesia) based on stimulus properties.
Area of Science:
- Psychology
- Neuroscience
- Pain Research
Background:
- Associative learning processes influence physiological responses.
- Environmental cues can become associated with pain or its relief.
Purpose of the Study:
- To review how stimuli, via associative processes, modify nociceptive responses.
- To provide an associative framework for understanding conditioned changes in pain sensitivity.
Main Methods:
- Literature review of studies on associative learning and pain.
- Analysis of conditioned analgesia, hyperalgesia, and tolerance to analgesics.
Main Results:
- Conditioned analgesia or hyperalgesia depends on the type of conditioned and unconditioned stimuli.
- Cues associated with pain reducers (e.g., opiates) can paradoxically increase pain sensitivity.
- Selective stimulus associations are key to altered pain perception.
Conclusions:
- Basic associative processes provide a framework for understanding conditioned changes in pain.
- Understanding these associations is crucial for pain management and treatment strategies.
Keywords:
2343 Learning & Memory2420 Learning & Motivation3360 Health Psychology & MedicineAnalgesiaConditioningHyperalgesiaMorphine tolerancePainMore Related Videos
Related Concept Videos
01:17Classical Conditioning in Daily Life
2.9K
Classical conditioning, a fundamental principle of associative learning, explains various phenomena observed in daily life, such as fear development, the placebo effect, taste aversion, and drug habituation. These applications demonstrate the profound impact of associative learning on human behavior and physiological responses.
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
2.9K
01:18Classical Conditioning
14.2K
Associative learning, a core principle in behavioral psychology, involves forming connections between events and facilitating learned responses. This concept is vividly illustrated by classical conditioning, a process extensively studied by the Russian physiologist Ivan Pavlov. Pavlov's pioneering research on dogs' digestive systems led to the discovery that behaviors can be learned through association, laying the groundwork for classical conditioning.
Ivan Pavlov observed that dogs...
Ivan Pavlov observed that dogs...
14.2K
01:25Analgesia and Pain Management
3.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
3.4K
01:15Real-World Application of Classical Conditioning
2.6K
Classical conditioning not only includes the initial pairing of stimuli but also extends to more complex forms, such as higher-order conditioning. Higher-order conditioning involves creating associations beyond the primary conditioned stimulus, resulting in a chain of conditioned responses.
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
2.6K
01:23Principles of Classical Conditioning
4.1K
Classical conditioning, as described by Ivan Pavlov, is a foundational concept in associative learning, where a neutral stimulus becomes capable of eliciting a conditioned response through association with an unconditioned stimulus. The process of acquisition, where this learning occurs, and the subsequent phenomena of contiguity, contingency, generalization, discrimination, extinction, and spontaneous recovery are crucial for a comprehensive understanding of classical conditioning.
During the...
During the...
4.1K
01:44Nociception
28.4K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
28.4K