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Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
Published on: July 19, 2024
Obesity, nutrition, and liver disease in children
Ariel E Feldstein1, Dana Patton-Ku, Kerri N Boutelle
1Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Rady Children's Hospital, 3020 Children's Way, San Diego, CA 92123, USA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California, San Diego, 9500 Gilman Drive, MC 0984, La Jolla, CA 92093, USA.
Abstract:
In this article, several aspects of childhood obesity are discussed, including epidemiology, associated metabolic complications, management strategies, and therapy with particular attention to the impact of obesity on the liver, resulting in nonalcoholic or metabolic fatty liver disease. The deleterious effects of obesity on the liver and health overall can be significantly impacted by a culture that fosters sustained nutritional improvement and regular physical activity. The current evidence is summarized supporting pharmacologic, behavioral, and dietary interventions for the management of obesity and fatty liver disease in children.
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