Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Working Memory

Working Memory

Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prediction modeling in transdiagnostic risk: results from the PROCAN study.

Brain imaging and behavior·2026

Same author

Feasibility of a parent-delivered attention and working memory intervention for early school-aged children born preterm.

Applied neuropsychology. Child·2026

Same author

Towards precision EEG connectomics: Evaluating the benefits of dense sampling.

Imaging neuroscience (Cambridge, Mass.)·2026

Same author

Links between parental internalizing disorder severity and default mode network connectivity in adolescent offspring.

Journal of psychiatric research·2026

Same author

Nonstandard Donors With Acceptable Risk for Infectious Disease in Kidney And Kidney-Pancreas Transplants: A Promising Solution.

Transplantation proceedings·2026

Same author

The Relationship Between Inhibitory Control of Attention and fMRI Functional Connectivity in Children With and Without ADHD.

Journal of attention disorders·2026

Search research articles

Related Experiment Video

Updated: May 5, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Intraparietal sulcus activity and functional connectivity supporting spatial working memory manipulation.

Signe Bray¹, Ramsha Almas², Aiden E G F Arnold³

¹Department of Psychiatry Hotchkiss Brain Institute Alberta Children's Hospital Research Institute.

Cerebral Cortex (New York, N.Y. : 1991)

|November 27, 2013

Summary

Spatial working memory (WM) involves the intraparietal sulcus (IPS). Maintaining spatial information engages contralateral IPS, while manipulating it involves bilateral IPS, particularly IPS1.

Keywords:

intraparietal sulcus spatial visuotopic working memory manipulation

More Related Videos

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Utilizing Electroencephalography Measurements for Comparison of Task-Specific Neural Efficiencies: Spatial Intelligence Tasks

Utilizing Electroencephalography Measurements for Comparison of Task-Specific Neural Efficiencies: Spatial Intelligence Tasks

Published on: August 9, 2016

Related Experiment Videos

Last Updated: May 5, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Utilizing Electroencephalography Measurements for Comparison of Task-Specific Neural Efficiencies: Spatial Intelligence Tasks

Utilizing Electroencephalography Measurements for Comparison of Task-Specific Neural Efficiencies: Spatial Intelligence Tasks

Published on: August 9, 2016

Area of Science:

Cognitive neuroscience
Neuroimaging
Human brain function

Background:

The intraparietal sulcus (IPS) is crucial for attention and working memory (WM).
Topographic maps of visual space exist along the IPS, akin to visual cortex retinotopy.
The differential roles of these IPS regions in spatial WM are not fully understood.

Purpose of the Study:

To investigate how visuotopic regions of the IPS are differentially involved in maintaining and manipulating spatial information in WM.
To map the involvement of specific IPS subregions (IPS0-4) in spatial WM tasks.

Main Methods:

Visuotopic mapping of the IPS in 26 participants to define regions of interest (IPS0-4).
A spatial WM task involving maintenance and mental rotation (manipulation) of a visual target.
Functional connectivity analyses to examine interactions between brain regions during WM tasks.
Control tasks including covert attention shifts and nonspatial manipulation (arithmetic).

Main Results:

Maintaining spatial WM targets preferentially engaged contralateral IPS.
Manipulating spatial information (mental rotation) engaged bilateral IPS, with peak activation in IPS1.
Functional connectivity revealed increased interactions between IPS and prefrontal cortex during manipulation, alongside interhemispheric communication.
Control tasks showed distinct patterns of IPS activation and connectivity compared to spatial WM manipulation.

Conclusions:

Specific visuotopic regions within the IPS play distinct roles in spatial WM maintenance versus manipulation.
Spatial WM manipulation involves broader bilateral IPS engagement and interactions with prefrontal and interhemispheric networks.
These findings refine our understanding of the neural basis of spatial working memory within the IPS.