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Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
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Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

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[Study on the correlation of lower extremity arterial vessels by ultrasonography and atherosclerosis detection

Rui Zhao1, Yin Li

  • 1Department of Ultrasound, Beijing No.2 Hospital,Beijing 100031, China.

Zhonghua Yi Xue Za Zhi
|November 29, 2013
PubMed

Insights

Ankle-brachial index (ABI) and Cardiac Ankle Vascular Index (CAVI) effectively screen for lower extremity arterial disease. These indicators, alongside ultrasound, improve detection of artery stenosis and atherosclerosis.

Area of Science:

  • Vascular Medicine
  • Diagnostic Imaging
  • Cardiovascular Research

Background:

  • Lower extremity arterial disease (LEAD) poses significant cardiovascular risk.
  • Early detection of LEAD is crucial for timely intervention and improved patient outcomes.

Purpose of the Study:

  • To investigate the correlation between lower extremity artery ultrasound findings and established atherosclerosis detection indicators.
  • To evaluate the efficacy of ankle-brachial index (ABI) and Cardiac Ankle Vascular Index (CAVI) in assessing LEAD.

Main Methods:

  • 320 patients were stratified into normal, mild, and severe lower extremity arterial disease groups based on ultrasonography.
  • Comparative analysis of ABI and CAVI values across the patient groups.
  • Logistic regression analysis was employed to identify risk factors for lower extremity atherosclerotic lesions.

Main Results:

  • Statistically significant differences in ABI were observed among the three groups (P < 0.05).
  • LEAD demonstrated a negative correlation with ABI and a positive correlation with CAVI (P = 0.000).
  • Age, gender, diabetes, and pulse pressure were identified as significant risk factors for lower extremity arterial disease.

Conclusions:

  • ABI and CAVI are reliable indicators for screening artery stenosis, occlusion, and atherosclerosis.
  • The combination of ABI, CAVI, and color Doppler ultrasonography enhances the diagnostic accuracy of lower extremity arterial disease.
Abstract

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